Friday, June 29, 2012

7 seconds put Errani in 2nd round; Federer wins

WIMBLEDON, England (AP) ? Count 'em: 7 seconds.

That's how long French Open runner-up Sara Errani "played" at Wimbledon on Wednesday against qualifier CoCo Vandeweghe of Rancho Santa Fe, Calif. ? enough time to wrap up a 6-1, 6-3 victory in the first round.

How's that possible? Because action was suspended by rain a night earlier, with the 10th-seeded Errani at match point as the 132nd-ranked Vandeweghe served.

When they resumed, after the customary several-minute warmup ritual of baseline strokes, volleys, overheads and serves, Vandeweghe tossed up a ball and hit it into the net. Moments later, she hit her second serve into the net, too, to complete the double-fault that ended the match, right then and there ? leaving both women smiling and spectators guffawing. Errani joined in the laughter as she packed away her racket bag, and kept right on giggling during her news conference.

Asked by an Italian reporter to recount what happened, Errani said, justifiably: "There's not much to tell."

Asked by another whether she'd bothered to take a shower, Errani assured him she planned to later.

"I had talked to my coach to plan what I wanted to do in the match," Errani said, "but there was no need."

All in all, it was exactly the sort of unusual happening that Day 3 kept producing in what's shaping up as a wet and wild week at the All England Club. Another: Prince Charles visited his nation's most famous tennis club, something he hadn't done in 42 years.

Four of the top 13 seeded women were sent packing Wednesday, including 2011 U.S. Open champion Sam Stosur, 2011 French Open champion Li Na, and former No. 1-ranked Caroline Wozniacki.

The fifth-seeded Stosur's 6-2, 0-6, 6-4 loss to 72nd-ranked Arantxa Rus of the Netherlands means Australia will have zero men or women in the third round for the first time since 1939.

"It's a pretty woeful performance by all of us," said Stosur, the last of nine Australians in the tournament.

Wozniacki, who hadn't departed any Grand Slam tournament in the first round in more than five years, blew two match points in the second set and was beaten 5-7, 7-6 (4), 6-4 by 37th-ranked Tamira Paszek of Austria. It was the first match of the fortnight played with the Centre Court's retractable roof closed.

"I had over two years where I was winning these matches," said No. 7 Wozniacki, who is dating 2011 U.S. Open golf champion Rory McIlroy and is still seeking her first major title. "I feel lately it's going the other way a little bit. It's not the first match this year where I have match points and not winning. You know, it's frustrating."

No. 11 Li lost to 52nd-ranked Sorana Cirstea of Romania 6-3, 6-4 in a second-round match, and 13th-seeded Dominika Cibulkova was beaten by 31st-ranked Klara Zakopalova of Czech Republic 6-4, 6-1 in the first round.

Adding to the anything-can-happen vibe, at least for the better part of an hour: No. 1 Maria Sharapova trailed 38th-ranked Tsvetana Pironkova throughout the first set, fended off five set points, and was ahead 7-6 (3), 3-1 when their second-round match was suspended by darkness.

That was one of four singles matches halted in progress, while four others were postponed entirely, adding to the backlog created by showers.

Before the rain came, Prince Charles sat in the Royal Box at Centre Court, watching six-time champion Roger Federer stumble once and awkwardly tweak his left knee but otherwise easily reach the third round by beating 68th-ranked Fabio Fognini of Italy 6-1, 6-3, 6-2.

"I'm fine. No pain, which is good," Federer said. "It could be dangerous with the left knee. I'm happy it was only basically a bruise to the ground, and not anything in the knee itself."

Federer and Fognini offered slightly stilted bows on their way off the court. Afterward, Federer chatted with and the Prince of Wales and Duchess of Cornwall for a few minutes, discussing tennis, polo and Federer's young twin daughters.

"They do brief you beforehand," said Federer, owner of a record 16 major championships, but none in the last 2 1/2 years. "I guess you don't do anything stupid. You behave. Obviously we were asked to bow, which is obviously no problem to do."

He said the royals "thought I played great ... which was unnecessary, but of course, I do appreciate it."

His performance was hardly out of the ordinary, of course. Nor was the 6-4, 6-4, 6-4 victory turned in by top-seeded and defending champion Novak Djokovic against 20-year-old American Ryan Harrison under the roof in the day's last match. Or straight-set wins by Andy Roddick to reach the second round and Kim Clijsters to get to the third.

Djokovic's second-round match against Harrison actually was much tighter than the score implies. Each man hit eight aces. Djokovic had one more winner, 31-30, and one more unforced error, 15-14. What made the difference? Djokovic converted 3 of 3 break points, and Harrison went 0 for 6.

"I was in trouble in the second set," Djokovic acknowledged. "It could have easily gone the other way."

But there were other interesting happenings.

Heather Watson, a British player ranked 103rd, became the first woman from the tournament's host country to reach the third round since 2002 by eliminating Jamie Hampton of the United States 6-1, 6-4.

Sloane Stephens, an unseeded 19-year-old American making her main-draw debut at the All England Club, saved five set points in the opener and wound up eliminating No. 23 Petra Cetkovska of the Czech Republic 7-6 (6), 4-6, 6-3. In the third set, Stephens was behind love-30 in four consecutive service games, before coming back to win each of them.

"I do still have some lapses," she said. "They're less now than I used to have in the past. I really don't get as upset when I lose points now. I'm not that emotional anymore."

No. 21-seeded Milos Raonic of Canada needed only slightly longer than Errani to finish off his rain-interrupted victory, coming back after a night's sleep to take the one game he was missing for a 6-4, 6-4, 6-4 defeat of Santiago Giraldo of Colombia. Raonic is scheduled to face Sam Querrey of the United States in the second round Thursday.

Errani is supposed to back out there Thursday, too, facing Anne Keothavong of Britain.

Seems safe to say Errani will need to put in a little more time and effort on court ? weather permitting, of course.

___

Follow Howard Fendrich on Twitter at http://twitter.com/HowardFendrich

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Novel Catalytic Function of MUC1 for the Development of Cancer Therapeutics (TID-242)

This newly discovered function of MUC1 presents a novel target for the development of new cancer therapies and diagnostics.

MUC1 is a membrane bound mucin protein that is overexpressed in 90% of epithelial carcinomas.? Due to its overexpression in a wide variety of tumors, MUC1 is considered an ideal target for the development of new diagnostics and therapeutics.? Researchers at the University of Nebraska Medical Center recently discovered a new function of MUC1.? Research led by Dr. Michael Hollingsworth has identified a ubiquitin interacting motif common to E2-ubiquitin conjugating enzymes within the C-terminal fragment of MUC1.? They have demonstrated that MUC1 is conjugated to ubiquitin via a cysteine residue only in the presence of an E1 enzyme and they have identified potential targets for MUC1-regulated ubiquitylation, such as the transcription factor c-Jun.? The development of inhibitors against this newly discovered E2 active site within MUC1 could become useful therapeutics for the treatment of cancer.? Furthermore new diagnostics can be developed for ubiquitinylated forms of MUC1 and targets of ubiquitinylation of MUC1, which would be extremely useful for cancer prognosis, monitoring cancer progression, and identifying appropriate therapeutic strategies.

Out-Licensing and/or Collaborative Development

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Thursday, June 21, 2012

1-in-4 Moms Now Pacifies Her Baby With a Cold, Hard Gadget [Parenting]

The Daily Mail (my favorite Paper of Record, if you hadn't guessed by now) is reporting that more than 1 in 4 mothers—27% to be precise—will hand her cranky or bored baby a cellphone—rather than, you know, something whose name literally means to pacify. More »


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Tuesday, June 19, 2012

Indian father beheads daughter over alleged affairs

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Christians United for Israel Withholds the Very Blessing They Claim to Want For Israel

Flag of IsraelInitially, let me tell you what I believe about the nation of Israel, so that I will not be misunderstood. (I?ve been called an anti-Semite twice in my life, both times for suggesting that people of Jewish descent need to hear the gospel.) I support the right of the nation of Israel to exist. I recognize that many Muslim nations and other anti-Semites deny that right and would like to wipe Israel off the map (and literally do so in children?s textbooks).

I believe Israel should aggressively defend herself against her enemies. I want justice to be done, and we should hold politicians accountable to behave righteously. Israel is an ally of the United States and should be treated accordingly. There is no question that many do target Israel because they think they are attacking God himself. The Holocaust occurred, and is worse than we thought.

Also, I try to be very careful about utilizing third party testimony against a brother or sister in Christ (or any other person for that matter). Accusations better be well-founded and from original and relevant sources. Most everything I want to say in this article is in response to the actual CUFI website or sources from within Christians United for Israel. I believe the goals and methods of CUFI are counter to the gospel and are draining resources from the only means of truly blessing the people of Israel: the preaching of the gospel. CUFI claims a membership of over a million people. How do I see the organization?

First, CUFI is devoid of the Christian gospel. Like many Christians in America, CUFI has replaced preaching with politics. In the end, they get everything backwards. Here is just a sampling:

Christians are called upon by CUFI to

?Learn, Pray and Share about Israel every day.?

?Therefore, CUFI On Campus equips and trains Christian students to become effective advocates for Israel on their campus, in their church, and in their community.?

?We hear over and over again from attendees who tell us that they never understood the Biblical mandate to support Israel and the Jewish people until they came to one of our events. Now, they write, the dots have been connected and they have a new focus and a new mission. (emphasis mine)?

It appears that CUFI has replaced ?Go and preach the gospel?first to the Jew? with ?go tell everybody about Israel.?

CUFI?s goal is to teach Americans about Israel, but there is NOTHING about teaching the people of Israel about Jesus. The Savior?s name is not mentioned once, even though He is the only true Hope of Israel. ?I did find the name Jesus mentioned once: one of the speakers for an event was named Jesus Infante (pronounced Hay-soos), and he was of Hispanic heritage.

Sadly, all of this is in keeping with the heretical doctrine that Pastor John Hagee (founder of CUFI) promotes, that the Jewish race can be saved apart from hearing and believing the gospel of Jesus Christ. He thinks Jews are saved by keeping the Law(!!), which they never were, not even during the Old Testament era. Abraham and David, like all other believers was saved by faith, according to Romans 4.

Here is Hagee?s viewpoint, according to the Houston Chronicle:

?I?m not trying to convert the Jewish people to the Christian faith,? he said?.

In fact, trying to convert Jews is a ?waste of time,? he said. ?The Jewish person who has his roots in Judaism is not going to convert to Christianity. There is no form of Christian evangelism that has failed so miserably as evangelizing the Jewish people. They (already) have a faith structure.?

Everyone else, whether Buddhist or Baha?i, needs to believe in Jesus, he says. But not Jews. Jews already have a covenant with God that has never been replaced by Christianity, he says.

?The Jewish people have a relationship to God through the law of God as given through Moses,? Hagee said. ?I believe that every Gentile person can only come to God through the cross of Christ. I believe that every Jewish person who lives in the light of the Torah, which is the word of God, has a relationship with God and will come to redemption.

?The law of Moses is sufficient enough to bring a person into the knowledge of God until God gives him a greater revelation. And God has not,? said Hagee, giving his interpretation of Romans 11:25. ?Paul abandoned the idea (of Jews knowing Christ). In the book of Romans, he said, `I am now going to go to the Gentiles from this time forward.? Judaism doesn?t need Christianity to explain its existence. But Christianity has to have Judaism to explain its existence.?

His position is a little unusual for evangelicals, who believe that the new covenant does supersede the old. Those who disagree with him are scathingly termed as ?replacement theologians.? The San Antonio pastor says such persons are anti-Semitic.

At its website, CUFI suggests 10 ways to bless Israel. Not one of them even hints at the gospel.

But the Bible teaches that Jews (and Gentiles) can be blessed today:

1. ?By not being offended at the gospel:

Romans 11:26 ??And blessed is he, whosoever shall not be offended in me

2. ?By turning from their sins

Acts 3:26? ?Unto you first God, having raised up his Son Jesus, sent him to bless you, in turning away every one of you from his iniquities.

3. ?By hearing the gospel.

Romans 15:29 ??And I am sure that, when I come unto you, I shall come in the fulness of the blessing of the gospel of Christ.

4. ?By being seated in heavenly places with Jesus.

Ephesians 1:3b ?Blessed be the God and Father of our Lord Jesus who hath blessed us with all spiritual blessings in heavenly places in Christ.

5. ?By reading the book of Revelation:

Revelation 1:3 Blessed is he that readeth, and they that hear the words of this prophecy, and keep those things which are written therein: for the time is at hand.

6. ?By dying in faith.

Revelation 14:13 ?Blessed [are] the dead which die in the Lord from henceforth:

Finally, I ask. If this is a Christian organization, and not simply a secular political organization hiding behind religious nomenclature, why is there no mention of Jesus, evangelism or the gospel? What kind of hope is there for anybody apart from Jesus? How does this bless Israel?

___________________________

In his book, With Christ in the Voting Booth, Shedlock addresses at length the relationship between nations, governments, and the gospel.

Tags: Anti-Semitism, Christians United for Israel, Evangelism, featured, Gospel of Jesus Christ, Israel, Jewish people, John Hagee

Category: Discernment, Doctrines of Grace, Evangelism, Foreign Policy, Islamic Issues, Soteriology

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Jack Osbourne says he has multiple sclerosis

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Live From The Microsoft Event In Los Angeles

microsoft-logo-retroWe're here at the Milk Studios in Hollywood for Microsoft's big mysterious Los Angeles media event. The off-duty actors and actresses are offering champagne flutes, the tech journalists are ignoring them while making sure their laptops work, and the electronic music is pumping as we all wait to see what is in store. TechCrunch will be liveblogging the entire event here, so stay tuned.

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